Preferential utilization of free cholesterol from high-density lipoproteins for biliary cholesterol secretion in man
CC Schwartz, LG Halloran, ZR Vlahcevic, DH Gregory… - Science, 1978 - science.org
CC Schwartz, LG Halloran, ZR Vlahcevic, DH Gregory, L Swell
Science, 1978•science.orgHigh-and low-density lipoproteins carrying free cholesterol labeled with 3H or 14C were
administered to a patient with a bile fistula. The free cholesterol from high-density
lipoproteins was more rapidly incorporated into biliary cholesterol than the free cholesterol
from low-density lipoproteins. These findings show that the liver in man selectively utilizes
and secretes the free cholesterol from a particular lipoprotein.
administered to a patient with a bile fistula. The free cholesterol from high-density
lipoproteins was more rapidly incorporated into biliary cholesterol than the free cholesterol
from low-density lipoproteins. These findings show that the liver in man selectively utilizes
and secretes the free cholesterol from a particular lipoprotein.
High- and low-density lipoproteins carrying free cholesterol labeled with 3H or 14C were administered to a patient with a bile fistula. The free cholesterol from high-density lipoproteins was more rapidly incorporated into biliary cholesterol than the free cholesterol from low-density lipoproteins. These findings show that the liver in man selectively utilizes and secretes the free cholesterol from a particular lipoprotein.
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