[HTML][HTML] Differential effects of HDL subpopulations on cellular ABCA1-and SR-BI-mediated cholesterol efflux
BF Asztalos, M de la Llera-Moya, GE Dallal… - Journal of lipid …, 2005 - ASBMB
Our objective was to evaluate the associations of individual apolipoprotein AI (apoA-I)-
containing HDL subpopulation levels with ABCA1-and scavenger receptor class B type I (SR-
BI)-mediated cellular cholesterol efflux. HDL subpopulations were measured by
nondenaturing two-dimensional gel electrophoresis from 105 male subjects selected with
various levels of apoA-I in preβ-1, α-1, and α-3 HDL particles. ApoB-containing lipoprotein-
depleted serum was incubated with [3 H] cholesterol-labeled cells to measure efflux. The …
containing HDL subpopulation levels with ABCA1-and scavenger receptor class B type I (SR-
BI)-mediated cellular cholesterol efflux. HDL subpopulations were measured by
nondenaturing two-dimensional gel electrophoresis from 105 male subjects selected with
various levels of apoA-I in preβ-1, α-1, and α-3 HDL particles. ApoB-containing lipoprotein-
depleted serum was incubated with [3 H] cholesterol-labeled cells to measure efflux. The …