Secondary lymphoid organ chemokines are elevated in the cerebrospinal fluid during central nervous system inflammation

M Pashenkov, M Söderström, H Link - Journal of neuroimmunology, 2003 - Elsevier
Secondary lymphoid organ chemokines have been implicated in chronic inflammation. Their
expression in the central nervous system (CNS) has not been studied. Here, levels of
secondary lymphoid organ chemokines CCL19 (Exodus-3, MIP-3β), CCL21 (Exodus-2,
6Ckine, SLC) and CXCL12 (SDF-1α) were analysed by ELISA in cerebrospinal fluid (CSF)
and plasma from patients with multiple sclerosis (MS); acute optic neuritis (ON) with
oligoclonal IgG in the CSF (ie, first bout of MS); acute ON without oligoclonal IgG (non-MS …