Age is the leading predictive factor for most of the chronic diseases that account for the
majority of morbidity, hospitalizations, healthcosts, andmortalityworldwide. These diseases
include Alzheimer disease and other neurodegenerative diseases, cardiovascular disease,
and most cancers. Chronological age is also the main risk factor for the geriatric syndromes,
including frailty and immobility as well as decreased physical resilience, which is manifested
by delayed or incomplete recoveryfromstressors, suchassurgery, hipfracture, and …