[HTML][HTML] Mice are not humans: the case of p53
M Fischer - Trends in Cancer, 2021 - cell.com
Trends in Cancer, 2021•cell.com
Mouse models represent powerful tools in cancer research that have influenced much of our
understanding of tumor development and our current anticancer strategies. Yet, central
signaling pathways differ considerably between mouse and human, including gene
regulatory networks (GRNs) of the most important tumor suppressor p53 and its oncogenic
sibling p63.
understanding of tumor development and our current anticancer strategies. Yet, central
signaling pathways differ considerably between mouse and human, including gene
regulatory networks (GRNs) of the most important tumor suppressor p53 and its oncogenic
sibling p63.
Mouse models represent powerful tools in cancer research that have influenced much of our understanding of tumor development and our current anticancer strategies. Yet, central signaling pathways differ considerably between mouse and human, including gene regulatory networks (GRNs) of the most important tumor suppressor p53 and its oncogenic sibling p63.
cell.com