Comparative transcriptome analysis of hESC-and iPSC-derived corneal endothelial cells

M Ali, SY Khan, F Kabir, JD Gottsch… - Experimental eye …, 2018 - Elsevier
The corneal endothelium (CE), a monolayer of hexagonal cells constitutes the innermost
layer of the cornea that is critical in maintaining clarity by mediating hydration through barrier
and pump functions. Corneal endothelial cells (CECs) have limited proliferative potential
and therefore generation of CECs has been undertaken by many groups. We previously
reported generation of CECs from peripheral blood mononuclear cell (PBMC)-originated,
induced pluripotent stem cells (iPSCs). In here, we extend our analysis through next …