The cornea is a multi-layered structure which allows fine refraction and provides both
resistance to external insults and adequate transparency. The corneal endothelium ensures
stromal hydration, failure of which, such as in Fuchs endothelial corneal dystrophy, after
trauma or in aging, may lead to loss of corneal transparency and induce blindness.
Currently, no efficient therapeutic alternatives exist except for corneal grafting. Thus corneal
tissue engineering represents a valuable alternative approach, which may overcome cornea …