Malignant potential of actinic keratoses and the controversy over treatment: a patient-oriented perspective
JM Dodson, J DeSpain, JE Hewett… - Archives of …, 1991 - jamanetwork.com
Dermatologists routinely treat actinic keratoses (AKs) based on the belief that these lesions
are premalignant and that treatment reduces morbidity. Marks et al 1 make a convincing
case for conservative management by suggesting that malignant transformation of AKs is
rare and that metastasis from such transformation is uncommon. They present their data as
the relationship between AKs detected during an initial visit and squamous cell carcinoma
(SCC) on examination 1 year later. Using this lesion-oriented approach, Marks and …
are premalignant and that treatment reduces morbidity. Marks et al 1 make a convincing
case for conservative management by suggesting that malignant transformation of AKs is
rare and that metastasis from such transformation is uncommon. They present their data as
the relationship between AKs detected during an initial visit and squamous cell carcinoma
(SCC) on examination 1 year later. Using this lesion-oriented approach, Marks and …
