Psoralen plus long-wave UV-A (PUVA) and bexarotene therapy: an effective and synergistic combined adjunct to therapy for patients with advanced cutaneous T-cell …
KS McGinnis, M Shapiro, CC Vittorio… - Archives of …, 2003 - jamanetwork.com
Background Multimodality biological response–modifier therapy that includes
photopheresis, interferon, and bexarotene is the standard of care in our institution for
advanced cutaneous T-cell lymphoma with peripheral blood involvement. We added
psoralen plus long-wave UV-A (PUVA) to this regimen in 5 patients with Sézary syndrome.
Observations All patients responded with decreased Sézary counts, resolution of
lymphadenopathy, and clearing of skin disease after the addition of PUVA. Adverse effects …
photopheresis, interferon, and bexarotene is the standard of care in our institution for
advanced cutaneous T-cell lymphoma with peripheral blood involvement. We added
psoralen plus long-wave UV-A (PUVA) to this regimen in 5 patients with Sézary syndrome.
Observations All patients responded with decreased Sézary counts, resolution of
lymphadenopathy, and clearing of skin disease after the addition of PUVA. Adverse effects …