Clinicopathological spectrum of mycosis fungoides

DV Kazakov, G Burg, W Kempf - Journal of the European …, 2004 - Wiley Online Library
DV Kazakov, G Burg, W Kempf
Journal of the European Academy of Dermatology and Venereology, 2004Wiley Online Library
Cutaneous lymphomas represent a heterogeneous group of T‐, NK‐and B‐cell neoplasms,
with mycosis fungoides (MF) being the most common subtype. MF has a plethora of
clinicopathological manifestations. Many variants of this lymphoma differ substantially from
the 'classical'Alibert–Bazin disease and are therefore sometimes referred to as
'atypical'forms of the disease. This review addresses the whole clinicopathological spectrum
of mycosis fungoides with respect to epidemiology, clinical, histopathological …
Abstract
Cutaneous lymphomas represent a heterogeneous group of T‐, NK‐ and B‐cell neoplasms, with mycosis fungoides (MF) being the most common subtype. MF has a plethora of clinicopathological manifestations. Many variants of this lymphoma differ substantially from the ‘classical’ Alibert–Bazin disease and are therefore sometimes referred to as ‘atypical’ forms of the disease. This review addresses the whole clinicopathological spectrum of mycosis fungoides with respect to epidemiology, clinical, histopathological, immunophenotypic and genotypic features and the clinical course and prognosis of its variants: classical, erythrodermic, follicular, syringotropic, bullous/vesicular, granulomatous, poikilodermic, hypo‐ and hyperpigmented, unilesional, palmoplantar, hyperkeratotic/verrucous, vegetating/papillomatous, ichthyosiform, pigmented purpura‐like, pustular and mucosal involvement in MF.
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