Leu-8/CD7 antigen expression by CD3+ T cells: comparative analysis of skin and blood in mycosis fungoides/Sézary syndrome relative to normal blood values
GS Wood, SR Hong, DT Sasaki, EA Abel… - Journal of the American …, 1990 - Elsevier
Deficiencies of Leu-8 and CD7 antigens are exhibited by CD3+ T cells in the skin lesions of
most patients with mycosis fungoides/Sézary syndrome. To determine whether these
antigenic abnormalities are limited to involved skin, we studied Leu-8/CD7 expression in 21
skin lesions of mycosis fungoides/Sézary syndrome obtained from 16 patients and
compared them with their peripheral blood leukocytes obtained concurrently. There was no
correlation between Leu-8/CD7 values in skin lesions versus blood. Blood values were …
most patients with mycosis fungoides/Sézary syndrome. To determine whether these
antigenic abnormalities are limited to involved skin, we studied Leu-8/CD7 expression in 21
skin lesions of mycosis fungoides/Sézary syndrome obtained from 16 patients and
compared them with their peripheral blood leukocytes obtained concurrently. There was no
correlation between Leu-8/CD7 values in skin lesions versus blood. Blood values were …